Bolsa de Investigação - Peroxisomal biogenesis
Peroxisomes are single membrane-bound organelles involved in many biochemical pathways. The vital importance of these organelles in human health and development is underscored by a group of genetic diseases - the peroxisomal biogenesis disorders (PBDs) - in which peroxisomes are partially or completely non-functional. PBDs are caused by mutations in genes encoding proteins involved in peroxisomal maintenance and inheritance, the so-called peroxins or PEX proteins.This project aims at characterizing in detail this protein sorting machinery. Several biochemical approaches will be used for this purpose, all of which are already implemented in the laboratory.
Área Científica: Bioquímica, Biologia ou relacionada
Local: Porto - See map
Habilitações: Mestrado
Experiência: final score ≥ 17. The candidate should have full autonomy in working in Molecular Biology and Biochemistry. Preference will be given to candidates with previous experience in cloning, recombinant protein production and purification, in vitro synthesis and characterization of radiolabeled proteins, and rat/mouse organelle isolation. Previous experience in the field of organelle structure/biochemistry/ biogenesis would be valued.
Início: 1 de Maio de 2017
Duração: 12 meses
Montante: 980€
Abertura Concurso: 6 de Abril de 2017
Deadline: CLOSED
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